White paper · 2024 · Precision in Practice
Manolo E. Beelke
Peer-reviewed article · 2019
Hupperts R, Smolders J, Vieth R, Holmøy T, Marhardt K, Schluep M, Killestein J, Barkhof F, Beelke M, Grimaldi L; SOLAR Study Group
Hupperts R, Smolders J, Vieth R, Holmøy T, Marhardt K, Schluep M, Killestein J, Barkhof F, Beelke M, Grimaldi L; SOLAR Study Group. Randomized trial of daily high-dose vitamin D3 in patients with RRMS receiving subcutaneous interferon beta-1a. Neurology. 2019;93(20):e1906-e1916. doi:10.1212/WNL.0000000000008445.
DOI: 10.1212/WNL.0000000000008445 PMID: 31594857
Peer-reviewed article · 2017
Beelke M E
Beelke M E. Towards A Personalized Medicine Approach for the Titration of Pharmacologic Treatments in Children with ADHD. J. of Pharmacol & Clin Res. 2017; 8(3): 555614. DOI: 10.19080/JPCR.2017.03.555614
DOI: 10.19080/JPCR.2017.03.555614
Peer-reviewed article · 2017
Beelke ME
Beelke ME. The Evolving Role of Medical Affairs: Opportunities for Discovery, Preclinical and Clinical Research. Journal for Clinical Studies. 2017 Volume 9 Issue 3: 20-24
Peer-reviewed article · 2017
Beelke, M. (2017).
Beelke, M. (2017). CPAP treatment promotes the closure of a patent foramen ovale in subjects with obstructive sleep apnea syndrome –Results from a pilot study. International Journal of Psychology and Neuroscience, 3(1), 1-21.
Peer-reviewed article · 2016
Beelke ME , Antonini P, Murphy MF
Beelke ME , Antonini P, Murphy MF. Evolving landscapes in multiple sclerosis research: adaptive designs and novel endpoints. Multiple Sclerosis and Demyelinating Disorders 2016 1:2.DOI: 10.1186/s40893- 016-0003
DOI: 10.1186/s40893-016-0003
Peer-reviewed article · 2015
Baranzini SE, Madireddy LR, Cromer A, D'Antonio M, Lehr L, Beelke M, Farmer P, Battaglini M, Caillier SJ, Stromillo ML, De Stefano N, Monnet E, Cree BA
Baranzini SE, Madireddy LR, Cromer A, D'Antonio M, Lehr L, Beelke M, Farmer P, Battaglini M, Caillier SJ, Stromillo ML, De Stefano N, Monnet E, Cree BA. Prognostic biomarkers of IFNb therapy in multiple sclerosis patients. Mult Scler. 2015 Jun;21(7):894-904. doi: 10.1177/1352458514555786. Epub 2014 Nov 12.
DOI: 10.1177/1352458514555786 PMID: 25392319
Letter to the Editor · 2012
Grimaldi L, Barkhof F, Beelke M, Burton J, Holmoy T, Hupperts R, Killestein J, Rieckmann P, Schluep M, Smolders J; SOLAR Study Group
Grimaldi L, Barkhof F, Beelke M, Burton J, Holmoy T, Hupperts R, Killestein J, Rieckmann P, Schluep M, Smolders J; SOLAR Study Group. A randomized trial of high-dose vitamin D2 in relapsing-remitting multiple sclerosis. Neurology. 2012;78(11):841.
Peer-reviewed article · 2011
Smolders J, Hupperts R, Barkhof F, Grimaldi LM, Holmoy T, Killestein J, Rieckmann P, Schluep M, Vieth R, Hostalek U, Ghazi-Visser L, Beelke M; on behalf of the SOLAR study group
Smolders J, Hupperts R, Barkhof F, Grimaldi LM, Holmoy T, Killestein J, Rieckmann P, Schluep M, Vieth R, Hostalek U, Ghazi-Visser L, Beelke M; on behalf of the SOLAR study group. Efficacy of vitamin D (3) as add-on therapy in patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon beta-1a: A Phase II, multicenter, double-blind, randomized, placebo-controlled trial. J Neurol Sci. 2011 May 25.
DOI: 10.1016/j.jns.2011.04.013 PMID: 21620416
Peer-reviewed article · 2008
Benedini S, Cortelli P, Caumo A, Terruzzi I, Beelke M , Perseghin G, Montagna P, Lugaresi E, Luzi L
Benedini S, Cortelli P, Caumo A, Terruzzi I, Beelke M , Perseghin G, Montagna P, Lugaresi E, Luzi L. Insulin resistance to both glucose and aminoacid metabolism in a patient with Fatal Familial Insomnia. Nutr Metab Cardiovasc Dis. 2008 Nov;18(9):e47-8.
DOI: 10.1016/j.numecd.2008.08.003 PMID: 18799296
Peer-reviewed article · 2006
Veiga S, Leonelli E, Beelke M, Garcia-Segura LM, Melcangi RC
Veiga S, Leonelli E, Beelke M, Garcia-Segura LM, Melcangi RC. Neuroactive steroids prevent peripheral myelin alterations induced by diabetes. Neurosci Lett. 2006 Jul 10;402(1-2):150-3. Epub 2006 Apr 19.
DOI: 10.1016/j.neulet.2006.03.058 PMID: 16626861
Peer-reviewed article · 2005
Lazzaro, C.; Beelke, M.
Lazzaro, C. and Beelke, M . Analisi costi -efficacia di 90Y -ibritumomab tiuxetano (Zevalin®) vs. terapie attualmente disponibili nel trattamento dei pazienti affetti da Linfoma Non-Hodgkin (LNH) refrattario o recidivato. Farmeconomia. Health economics and therapeutic pathways. 2005, 6(4), 317-332. doi: https://doi.org/10.7175/fe.v6i4.845
DOI: 10.7175/fe.v6i4.845
Peer-reviewed article · 2004
De Carli F, Nobili L, Beelke M, Watanabe T, Smerieri A, Parrino L, Terzano MG, Ferrillo F
De Carli F, Nobili L, Beelke M, Watanabe T, Smerieri A, Parrino L, Terzano MG, Ferrillo F. Quantitative analysis of sleep EEG microstructure in the time-frequency domain.Brain Res Bull. 2004 Jun 30;63(5):399-405.
DOI: 10.1016/j.brainresbull.2003.12.013 PMID: 15245767
Peer-reviewed article · 2004
Garbarino S, Mascialino B, Penco MA, Squarcia S, De Carli F, Nobili L, Beelke M, Cuomo G, Ferrillo F
Garbarino S, Mascialino B, Penco MA, Squarcia S, De Carli F, Nobili L, Beelke M, Cuomo G, Ferrillo F. Professional shift-work drivers who adopt prophylactic naps can reduce the risk of car accidents during night work. Sleep. 2004 Nov 1;27(7):1295-302.
DOI: 10.1093/sleep/27.7.1295 PMID: 15586782
Peer-reviewed article · 2004
Rizzo P, Beelke M , De Carli F, Canovaro P, Nobili L, Robert A, Fornaro P,Tanganelli P, Regesta G, Ferrillo F
Rizzo P, Beelke M , De Carli F, Canovaro P, Nobili L, Robert A, Fornaro P,Tanganelli P, Regesta G, Ferrillo F. Modifications of sleep EEG induced by chronic vagus nerve stimulation in patients affected by refractory epilepsy. Clin Neurophysiol. 2004 Mar;115(3):658-64
DOI: 10.1016/j.clinph.2003.10.026 PMID: 15036062
Peer-reviewed article · 2004
Nobili L, Baglietto MG, Beelke M, De Carli F, Di Comite R, Fiocchi I, Rizzo P, Veneselli E, Savoini M, Zanotto E, Ferrillo F
Nobili L, Baglietto MG, Beelke M, De Carli F, Di Comite R, Fiocchi I, Rizzo P, Veneselli E, Savoini M, Zanotto E, Ferrillo F. Impairment of the production of delta sleep in anorectic adolescents. Sleep. 2004 Dec 15;27(8):1553-9.